genex®

Discover a precisely balanced β-tricalcium phosphate/calcium sulfate hemihydrate compound that is the perfect partner for your trauma and non-unions – complementing the body’s natural healing processes, then vanishing without a trace.

Perfect partner for your trauma and non-unions

genex is a catalyst for bone healing. It complements the body’s natural healing processes and encourages normal bone structure to be restored at a steady rate. Over 12 months, the graft matrix is completely absorbed and replaced by bone 1,2. No foreign artifacts are left behind to impair structural integrity.

  • Approved for bony voids and defects that are not intrinsic to structural stability.
  • An innovative, versatile choice that supports natural healing, then vanishes without a trace.

GenexTemp.png

 

References: 1. Yang, H.L., et al., Bone healing response to a synthetic calcium sulfate/beta-tricalcium phosphate graft material in a sheep vertebral body defect model. J Biomed Mater Res B Appl Biomater, 2012. 100B(7): p. 1911-21. 2. Data on file, Mr Nissar & Mr Gopal.

For indications, contraindications, warnings and precautions see Instructions for Use. ©2017, Biocomposites and genex are registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorised copying, reproduction, distributing or re-publication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd.

Patents granted: EP 1390086 B1, US 8632796, CN ZL02809194.9, US 8496955.

 

 

Designed to be completely absorbed and leave no trace

genex is a precisely balanced β-tricalcium phosphate/calcium sulfate hemihydrate compound with distinct design properties:

  • Contains no hydroxyapatite (HA)
  • Negatively charged surface chemistry

genex provides a powerful scaffold for accelerated bone restoration and helps to hinder soft tissue ingrowth:

  • Fully absorbed within 12 months
  • Enhances osteogenic response
  • Restores strong healthy bone

Completely absorbed within 12 months1,2

GenexImplantation.png  Genex6Weeks.png   Genex8Weeks.png Genex36Weeks.png
 genex Implantation  6 Weeks  8 Weeks  36 Weeks

 

genex contains no hydroxyapatite. HA can only be absorbed  at 1–2% per year5

(Large animal model. Decalcified histology H&E stain)

Enhances the osteogenic response to accelerate bone growth – 5x normal levels5

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Restores strong healthy bone within a clinically relevant timeframe2,3

70700027A_GeneX_Insert_Plateau_Presentation_CT scan_157x192.png 70700027A_GeneX_Insert_Plateau_Post operative_157x192.png 70700027A_Genex_Brochure_Inside_PAGE_5_15 months_157x192.png
Tibial plataeu fracture Post op 15 months

genex restores bone to normal trabecular structure in 36 weeks1

References: 1.Yang, H.L., et al., Bone healing response to a synthetic calcium sulfate/beta-tricalcium phosphate graft material in a sheep vertebral body defect model. J Biomed Mater Res B Appl Biomater, 2012. 100B(7): p. 1911-21.2.Data on file, Mr A Nissar and Mr S Gopal.3.Data on file, Mr HK Sharma.4.Pina, S. and J.M.F. Ferreira, Bioresorbable Plates and Screws for Clinical Applications: A Review. Journal of Healthcare Engineering, 2012. 3(2).5.Cooper, J.J., J.A. Hunt, and F. Pu, Enhancing the Osteogenic Potential of Bioabsorbable Implants through Control of Surface Charge., in Society for Biomaterials 2007 Annual Meeting. 2007: Chicago, Illinois, USA.

For indications, contraindications, warnings and precautions see Instructions for Use. ©2017, Biocomposites and genex are registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorised copying, reproduction, distributing or re-publication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd.

Patents granted: EP 1390086 B1, US 8632796, CN ZL02809194.9, US 8496955.

 

Versatility at your fingertips

genex is versatile and easy to prepare. It comes as a paste or putty in a range of volumes. The paste sets within 15 minutes, at body temperature, and can be digitally implanted or injected in difficult-to-reach sites, or minimally invasive procedures.

 70700027A_Genex_Brochure_Inside_PAGE_6_GeneX_GroupShot_500x250.png

A range of surgical applications
PRODUCTPASTE VOLUMESETTING TIMESCATALOGUE REF

genex
Setting paste for moulding, 
injecting and packing

5 cc 15 minutes approx. 900–005
10 cc 900–010
       
genex ds
Setting paste for difficult-to-reach 
surgical sites
2.5 cc 15 minutes approx. 980–002
5 cc 980–005
       
genex putty
Non-setting putty that 
requires no mixing
2.5 cc Non-setting 920–002
5 cc 920–005
10 cc 920–010

 

For indications, contraindications, warnings and precautions see Instructions for Use. ©2017, Biocomposites and genex are registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorised copying, reproduction, distributing or re-publication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd.

Patents granted: EP 1390086 B1, US 8632796, CN ZL02809194.9, US 8496955.

 

Transform outcomes

genex offers successful long-term outcomes across a range of surgical applications, including tibial plateau fractures and long-bone non-unions

Use of genex in tibial plateau fracture

Patient presented with: Comminuted Schatzker type II fracture of right leg. X-ray examination revealed 2 large fragments and several small fragments.

Outcome: At 15 months’ follow-up the fracture had healed and knee was stable, with a range of motion of 0–130°. genex had completely absorbed.

Click to read full case study

 

 

to-genex-cs2.pngUse of genex in proximal femur fracture

Patient presented with: Failed intramedullary nailing of an extracapsular neck of femur fracture. Patient complained of prominent metalwork and pain.

Outcome: At 12 months’ follow-up the fracture had healed with complete absorption of genex. Patient had a good range of hip motion and was able to walk and manage stairs.

Click to read full case study

 

 

Use of genex in distal tibia non-union

Patient presented with: Healed fibula with a non-union of the distal tibia and a fracture through the nail, 19 months after the initial operation.

Outcome: At 10 months’ follow-up the non-union had healed completely, patient had fully recovered and was scheduled to have the intramedullary nail removed.

Click to read full case study

 

 

 

 

For indications, contraindications, warnings and precautions see Instructions for Use. ©2017, Biocomposites and genex are registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorised copying, reproduction, distributing or re-publication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd.

Patents granted: EP 1390086 B1, US 8632796, CN ZL02809194.9, US 8496955.

 

genex

Power to restore without leaving a trace

The science of genex

Engineered for bone healing

How to prepare

genex ds

Case studies

Read case studies for trauma

Resources

  • genex brochure
  • genex preparation guide

Find out more