STIMULAN®

STIMULAN is a pharmaceutical-grade calcium sulfate that is the perfect partner for your infection management strategy – helping you to improve surgical outcomes and lower overall costs of care.

Perfect partner for your infection management strategy

STIMULAN is a truly absorbable calcium sulfate, specifically designed to complement your dead space and infection management strategies.1

  • Approved for placement directly at the site of infection

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Calcium sulfate uniquely recrystallised to transform outcomes

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Reference: 1. Biocomposites Ltd, STIMULAN Instructions for Use.

For indications, contraindications, warnings and precautions see Instructions for Use.  The treating physician is responsible for deciding the type and quantity of antibiotic used.  Concurrent use of locally administered antibiotics may affect setting time.

The mixing of antibiotics with the STIMULAN Kit / STIMULAN Rapid Cure device is considered off-label usage of the medicinal product. To do so is at the professional risk of the surgeon / healthcare professional.

This page may include the use of STIMULAN or techniques that go beyond the current clearance/ approval granted by the relevant regulatory authority. Please contact your local representative for further information.

©2017, Biocomposites and STIMULAN are registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorised copying, reproduction, distributing or republication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd. 

Patents granted: GB2367552, EP 1204599 B1, US 6780391, EP 2594231 B1, US 8883063, CN ZL201210466117.X, GB2496710

Patents pending: GB1502655.2, EP 16154210.5, US 15/040075, CN 201610089710.5, US 15/288328.

Recrystallised for improved clinical performance

STIMULAN has a unique crystal structure and properties.1,2

  • Controlled purity
  • Physiologic pH level
  • Hydrophilicity

Only STIMULAN undergoes a patented recrystallisation process that starts with pharmaceutical-grade reagents and results in its consistent and reliable performance.1–8

  • Truly absorbable at an optimal rate
  • No third body damage
  • Low levels of drainage

Truly absorbable and totally synthetic calcium sulfate – absorbs at an optimal rate1–5,8

Leaves no nidus for infection.

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Post-operative
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1 month
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11 weeks
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6 months

Low levels of drainage2–3, 6–7, 10–12

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No third body damage13
Less scratching than competitor calcium sulfate and PMMA.

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For indications, contraindications, warnings and precautions see Instructions for Use.  The treating physician is responsible for deciding the type and quantity of antibiotic used.  Concurrent use of locally administered antibiotics may affect setting time.

The mixing of antibiotics with the STIMULAN Kit / STIMULAN Rapid Cure device is considered off-label usage of the medicinal product. To do so is at the professional risk of the surgeon / healthcare professional.

This page may include the use of STIMULAN or techniques that go beyond the current clearance/ approval granted by the relevant regulatory authority. Please contact your local representative for further information.

©2017, Biocomposites and STIMULAN are registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorised copying, reproduction, distributing or republication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd. 

Patents granted: GB2367552, EP 1204599 B1, US 6780391, EP 2594231 B1, US 8883063, CN ZL201210466117.X, GB2496710

Patents pending: GB1502655.2, EP 16154210.5, US 15/040075, CN 201610089710.5, US 15/288328.

Case-by-case flexibility

STIMULAN can be used in three sizes of bead, as a paste or for injection. Its hydrophilic properties and options of rapid or standard setting times make it quick and easy to prepare – helping you to adapt to each case as is merited. 

 

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Flexible formats to optimise dead space management

STIMULANPASTE VOLUMEBEAD VOLUMESETTING TIMEORDER CODES
Kit (standard setting)

Fully injectable paste
with individual bead kit
5 cc 10 cc

Approx.

8 minutes

600–005
10 cc 20 cc 600–010
         
Rapid Cure 

Rapid setting paste
with individual bead kit
5 cc 12.5 cc

Approx.

4 minutes

620–005
10 cc 25 cc 620–010
20 cc 50 cc 620–020

 

For indications, contraindications, warnings and precautions see Instructions for Use.  The treating physician is responsible for deciding the type and quantity of antibiotic used.  Concurrent use of locally administered antibiotics may affect setting time.

The mixing of antibiotics with the STIMULAN Kit / STIMULAN Rapid Cure device is considered off-label usage of the medicinal product. To do so is at the professional risk of the surgeon / healthcare professional.

This page may include the use of STIMULAN or techniques that go beyond the current clearance/ approval granted by the relevant regulatory authority. Please contact your local representative for further information.

©2017, Biocomposites and STIMULAN are registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorised copying, reproduction, distributing or republication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd. 

Patents granted: GB2367552, EP 1204599 B1, US 6780391, EP 2594231 B1, US 8883063, CN ZL201210466117.X, GB2496710

Patents pending: GB1502655.2, EP 16154210.5, US 15/040075, CN 201610089710.5, US 15/288328.

Transform outcomes

STIMULAN can transform outcomes in infected non-unions, osteomyelitis and periprosthetic joint infection.

 

diabetic foot_eu-01.pngTransform osteomyelitis in diabetic foot

Patient presented with: persistent osteomyelitis and interphalangeal joint destruction of left hallux. He was already receiving treatment for Charcot arthropathy to his right foot.

Outcome: 2 weeks post-operatively, the toe reduced in size. At the 16-month x-ray the patient was infection-free and amputation had been avoided. STIMULAN was seen to have completely absorbed at 4 months.

Click to read full case study

 

trauma_eu.01.pngTransform infected trauma

Patient presented with: infected femoral nail and non-union of left femur with persistent discharging wounds proximally and distally.

Outcome: At 7 months follow-up there was a complete healing of the non-union and at 1 year patient remains infection free, walking with no pain.

Click to read full case study

arthroplasty_eu-01.pngTransform infected revision arthroplasty

Patient presented with: infected total knee replacement 2 years after primary procedure.

Outcome: At 1 year follow-up the patient remains infection free and is under regular follow-up.

Click to read full case study

 

Dr Wassef case study

Infected hip revision with STIMULAN beads

Dr Webb case study

Bilateral high energy femoral fractures with STIMULAN beads

Testimonials

Hear what surgeons have to say about STIMULAN

Testimonials

Hear what surgeons have to say about STIMULAN

Testimonials

Hear what surgeons have to say about STIMULAN

How to prepare

STIMULAN Rapid Cure

Case studies

Read case studies for trauma

Case studies

Read case studies for musculoskeletal infections

Resources

  • STIMULAN brochure
  • STIMULAN preparation guide
  • FAQs

Find out more