STIMULAN is indicated for use in musculoskeletal defects created by surgery, a cyst, a tumour, osteomyelitis or traumatic injury. STIMULAN is not intended to provide structural support during the healing process. It can be used at an infected site.
Contraindications for STIMULAN can be found in the IFU. These include contraindications for filling defects which are intrinsic to the stability of the bony structure, renal compromised patients, hypercalcaemia, severe vascular or neurological disease, uncontrolled diabetes, pregnancy, severe degenerative bone disease and uncooperative patients who can't or won’t follow post-operative instructions including individuals who abuse alcohol or drugs.
STIMULAN is already used in over 20,000 cases a year. We are happy to introduce physicians to an appropriate surgeon if they would like to have a peer to peer conversation.
This is an area of ongoing research but biomechanical testing (pin on plate) indicates that STIMULAN does not significantly scratch implant grade cobalt chrome and does not lead to increased wear of high density polyethylene components, when compared to a control with no STIMULAN present.
STIMULAN is an osteoconductive material and is not osteoinductive or osteogenic in nature. Biocomposites has published a range of clinical data indicating a minimal risk of HO if implanted in soft tissue.
STIMULAN is a pharmaceutical-grade, synthetic calcium sulfate. The physical and chemical properties are tightly controlled through Biocomposites’ patented recrystallisation process to ensure optimum purity. Evidence has shown that STIMULAN is associated with reduced drainage rates when compared to non-synthetic calcium sulfates. Naturally occurring mineral sources of calcium sulfate can contain non absorbing earth impurities, may be of acidic pH and hydrophobic in nature, and are often linked to significant problems with wound healing and drainage.
Wound drainage may occur with any implanted material. STIMULAN has a low documented occurrence of wound drainage. It may be attributed to several factors including patient health and surgical methods e.g. 1) large volumes of STIMULAN beads placed in a concentrated area may cause stretching of the tissue envelope during normal range of motion and leakage at the wound site, 2) patients with comorbidities have a much greater probability of draining due to their poor tissue quality, which may not permit a watertight seal. To reduce the risk of drainage ensure complete soft tissue coverage and/or containment is achieved.