genex®

The only remaining evidence of the trauma

Perfect partner for your trauma and non-unions

genex is a catalyst for bone healing. It complements the body’s natural healing processes and encourages normal bone structure to be restored at a steady rate. Over 12 months, the graft matrix is completely absorbed and replaced by bone.1,2 No foreign artifacts are left behind to impair structural integrity.

  • Approved for bony voids and defects that are not intrinsic to structural stability.

Designed to be completely absorbed and leave no trace

genex is a precisely balanced β-tricalcium phosphate/calcium sulfate hemihydrate compound with distinct design properties:

  • Contains no hydroxyapatite (HA)
  • Negatively charged surface chemistry

genex provides a powerful scaffold for accelerated bone restoration and helps to hinder soft tissue ingrowth:

  • Fully absorbed within 12 months1,2
  • Enhances osteogenic response3
  • Restores strong healthy bone2,4
Completely absorbed within 12 months

genex contains no hydroxyapatite. HA can only be absorbed at 1–2% per year5

Large animal model. Decalcified histology H & E stain

Implantation
8 weeks
16 weeks
36 weeks
Restores strong healthy bone within a clinically relevant timeframe

genex restores bone to normal trabecular structure in 36 weeks1

Tibial plateau fracture
Post-operative
15 months
Enhances the osteogenic response to accelerate bone growth – 5x normal levels

 

Versatility at your fingertips

genex is versatile and easy to prepare. It comes as a paste or putty in a range of volumes. The paste sets within 15 minutes, at body temperature, and can be digitally implanted or injected in difficult-to-reach sites, or minimally invasive procedures.

genex® products
genex®

Setting paste for molding, injecting and packing

  • Available in 5cc and 10cc packs
  • Sets in approximately 15 minutes
genex® ds

Setting paste for difficult to reach surgical sites

  • Available in 2.5cc and 5cc packs
  • Sets in approximately 15 minutes
genex® putty

Non-setting putty that requires no mixing

  • Available in 2.5cc, 5cc and 10cc packs
  • Non-setting
Videos
genex - power to restore without leaving a trace
genex - power to restore without leaving a trace
How to prepare genex
How to prepare genex ds
The science of genex
Case studies

References and regulatory statements

1.  Yang, H.L., et al., Bone healing response to a synthetic calcium sulfate/beta-tricalcium phosphate graft material in a sheep vertebral body defect model. J Biomed Mater Res B Appl Biomater, 2012. 100B(7): p. 1911-21. 2. Data on file, Mr Nissar & Mr Gopal. 3. Cooper, J.J., J.A. Hunt, and F. Pu, Enhancing the Osteogenic Potential of Bioabsorbable Implants through Control of Surface Charge., in Society for Biomaterials 2007 Annual Meeting. 2007: Chicago, Illinois, USA. 4. Data on file, Mr HK Sharma. 5. Pina, S. and J.M.F. Ferreira, Bioresorbable Plates and Screws for Clinical Applications: A Review. Journal of Healthcare Engineering, 2012. 3(2)

For indications, contraindications, warnings and precautions see Instructions for Use.

©2019, Biocomposites, genex and Power to Restore are trademarks/registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorised copying, reproduction, distributing or re-publication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd.

Patents granted: EP 1390086 B1, US 8632796, CN ZL02809194.9, US 8496955

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