Transform osteomyelitis in diabetic foot

Courtesy of Mr Robert Morley, Specialist Registrar in Podiatric Surgery, Derbyshire, UK
Products: STIMULAN®
Clinical particulars
67-year-old male patient with Type 2 diabetes presented with a 1 year history of a right foot ulcer and symptoms of infection with osteomyelitis caused by Staphylococcus aureus. Previous treatment involved 9 months I.V. antibiotics and regular re-dressing with no improvement. Most oral antibiotics were contraindicated due to a history of Clostridium difficile.  
Treatment
After surgical debridement and thorough irrigation, STIMULAN mixed with gentamicin and vancomycin was placed in the wound site. A 3 day perioperative course of I.V. antibiotic therapy was administered based on a bone biopsy with no other antibiotics used post-operatively.  
Outcome
5 weeks post-surgery the surgical wound and ulcer had healed and erythema and swelling had fully reduced. ESR and CRP were within normal limits and x-rays showed no deterioration. At 3 months the patient was mobilising normally, free from infection and STIMULAN had fully absorbed. Implantation of STIMULAN negated the need to perform a full forefoot amputation.   Note: See STIMULAN page for regulatory statements. MA0159R1
Evidence

Listed below are 4 of the most relevant articles for this piece of evidence but there is much more unrivalled evidence to explore on our Evidence page.

Explore evidence