The only remaining evidence of the trauma

Perfect partner for your trauma and non-unions

genex is a catalyst for bone healing. It complements the body’s natural healing processes and encourages normal bone structure to be restored at a steady rate. Over 12 months, the graft matrix is completely absorbed and replaced by bone.1,2 No foreign artifacts are left behind to impair structural integrity.

  • Approved for bony voids and defects that are not intrinsic to structural stability.

Designed to be completely absorbed and leave no trace

genex is a precisely balanced β-tricalcium phosphate/calcium sulfate hemihydrate compound with distinct design properties:

  • Contains no hydroxyapatite (HA)
  • Negatively charged surface chemistry

genex provides a powerful scaffold for accelerated bone restoration and helps to hinder soft tissue ingrowth:

  • Fully absorbed within 12 months1,2
  • Enhances osteogenic response3
  • Restores strong healthy bone2,4
Completely absorbed within 12 months

genex contains no hydroxyapatite. HA can only be absorbed at 1–2% per year5

Large animal model. Decalcified histology H & E stain

8 weeks
16 weeks
36 weeks
Restores strong healthy bone within a clinically relevant timeframe

genex restores bone to normal trabecular structure in 36 weeks1

Tibial plateau fracture
15 months
Enhances the osteogenic response to accelerate bone growth – 5x normal levels

Versatility at your fingertips

genex is versatile and easy to prepare. It comes as a paste or putty in a range of volumes. The paste sets within 15 minutes, at body temperature, and can be digitally implanted or injected in difficult-to-reach sites, or minimally invasive procedures.

genex® products

Setting paste for molding, injecting and packing

  • Available in 5cc and 10cc packs
  • Sets in approximately 15 minutes
genex® ds

Setting paste for difficult to reach surgical sites

  • Available in 2.5cc and 5cc packs
  • Sets in approximately 15 minutes
genex® Bone Graft Substitute

Setting paste for molding, injecting and packing

  • Available in 5cc and 10cc packs
  • Sets in approximately 15 minutes
genex® putty

Non-setting putty that requires no mixing

  • Available in 2.5cc, 5cc and 10cc packs
  • Non-setting
genex - power to restore without leaving a trace
How to prepare genex
How to prepare genex ds
The science of genex

Listed below are 4 of the most relevant articles for this product but there is much more unrivalled evidence to explore on our Library page.

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Frequently asked questions
What is genex indicated for?

genex is indicated only for bony voids or defects/gaps that are not intrinsic to the stability of the bony structure.

genex is indicated to be gently packed into voids or defects of the skeletal system (i.e. long bones, extremities, spine and pelvis).

genex resultant paste can be injected, digitally packed into the bone void to cure in situ or moulded into solid implants that are to be gently packed into the defect. The bony defects or cavities may be surgically created or the result of traumatic injury.

genex provides a bone graft substitute that resorbs and is replaced with bone during the healing process.

What is genex contraindicated for?

• Filling of defects which are intrinsic to the stability of the bony structure
• Severe vascular or neurological disease
• Uncontrolled diabetes
• Severe degenerative bone disease
• Pregnancy
• Uncooperative patient who can’t or won’t follow post-operative instructions including individuals who
abuse drugs or alcohol
• Hypercalcaemia

How long does genex take to absorb in bone?

genex is completely absorbed within 12 months.

What is the compressive strength of genex?

genex has been shown to have a compressive strength approximately 3x stronger than cancellous bone when fully set (15 MPa). The compressive strength reduces as genex is absorbed.

References and regulatory statements

1.  Yang, H.L., et al., Bone healing response to a synthetic calcium sulfate/beta-tricalcium phosphate graft material in a sheep vertebral body defect model. J Biomed Mater Res B Appl Biomater, 2012. 100B(7): p. 1911-21. 2. Data on file, Mr Nissar & Mr Gopal. 3. Cooper, J.J., J.A. Hunt, and F. Pu, Enhancing the Osteogenic Potential of Bioabsorbable Implants through Control of Surface Charge., in Society for Biomaterials 2007 Annual Meeting. 2007: Chicago, Illinois, USA. 4. Data on file, Mr HK Sharma. 5. Pina, S. and J.M.F. Ferreira, Bioresorbable Plates and Screws for Clinical Applications: A Review. Journal of Healthcare Engineering, 2012. 3(2)

For indications, contraindications, warnings and precautions see Instructions for Use.

©2019, Biocomposites, genex and Power to Restore are trademarks/registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorized copying, reproduction, distributing or re-publication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd.

Patents granted: EP 1390086 B1, US 8632796, CN ZL02809194.9, US 8496955