genex®

The only remaining evidence of the trauma

Perfect partner for your trauma and non-unions

genex is a catalyst for bone healing. It complements the body’s natural healing processes and encourages normal bone structure to be restored at a steady rate. Over 12 months, the graft matrix is completely absorbed and replaced by bone.1,2 No foreign artifacts are left behind to impair structural integrity.

  • Cleared for bony voids and defects that are not intrinsic to structural stability of the bony structure.

Designed to be completely absorbed and leave no trace

genex is a precisely balanced β-tricalcium phosphate/calcium sulfate hemihydrate compound with distinct design properties:

  • Contains no hydroxyapatite (HA)
  • Negatively charged surface chemistry

genex provides a powerful scaffold for accelerated bone restoration and helps to hinder soft tissue ingrowth:

  • Fully absorbed within 12 months1,2
  • Enhances osteogenic response3
  • Restores strong healthy bone2,4
Completely absorbed within 12 months

genex contains no hydroxyapatite. HA can only be absorbed at 1–2% per year5

Large animal model. Decalcified histology H & E stain

Implantation
8 weeks
16 weeks
36 weeks
Restores strong healthy bone within a clinically relevant timeframe

genex restores bone to normal trabecular structure in 36 weeks1

Tibial plateau fracture
Post-operative
15 months
Enhances the osteogenic response to accelerate bone growth – 5x normal levels

Versatility at your fingertips

genex is versatile and easy to prepare. The paste sets within 15 minutes at body temperature, and can be digitally implanted or injected in difficult-to-reach sites or minimally invasive procedures. genex has a working time of 3 minutes and is drillable after 15 minutes.

genex® products
genex Bone Graft Substitute

Setting paste for molding, injecting and packing

  • Available in 5cc and 10cc packs
  • Sets in approximately 15 minutes
Videos
genex - power to restore without leaving a trace
genex - power to restore without leaving a trace
How to prepare genex
The science of genex
Case studies

References and regulatory statements

1.  Yang, H.L., et al., Bone healing response to a synthetic calcium sulfate/beta-tricalcium phosphate graft material in a sheep vertebral body defect model. J Biomed Mater Res B Appl Biomater, 2012. 100B(7): p. 1911-21. 2. Data on file, Mr Nissar & Mr Gopal. 3. Cooper, J.J., J.A. Hunt, and F. Pu, Enhancing the Osteogenic Potential of Bioabsorbable Implants through Control of Surface Charge., in Society for Biomaterials 2007 Annual Meeting. 2007: Chicago, Illinois, USA. 4. Data on file, Mr HK Sharma. 5. Pina, S. and J.M.F. Ferreira, Bioresorbable Plates and Screws for Clinical Applications: A Review. Journal of Healthcare Engineering, 2012. 3(2)

For indications, contraindications, warnings and precautions see Instructions for Use.

©2019, Biocomposites, genex and Power to Restore are trademarks/registered trademarks of Biocomposites Ltd. All rights reserved. No unauthorized copying, reproduction, distributing or re-publication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd.

Patents granted: EP 1390086 B1, US 8632796, CN ZL02809194.9, US 8496955

MA0118R2 & MA0285R1