Case study

Infected revision THA

Courtesy of Dr. Andrew Wassef Orthopaedic Surgeon

Clinical Particulars

84-year-old male presented with a painful left hip 18 years after a total hip arthroplasty procedure. An extensive examination was conducted to determine the source of the pain. Labs and aspiration were negative for infection. Severe polyethylene wear with extensive resultant osteolysis of the pelvis and proximal femur was identified. A CT scan also demonstrated an unsupportive posterior column with extensive osteolysis of the anterior wall.


Surgical management was elected with a complex revision of the left THA and pelvic reconstruction using a custom tri-flange cage. STIMULAN beads were used to fill the dead space in the hip and pelvis. Intraoperative cultures were positive for Enterococcus despite pre-operative examination results. Antibiotic treatment was administered based on the sensitivities of the organism and I.V. antibiotics were continued for 6 weeks following surgery.


The patient had a successful recovery with well-fixed components, complete absorption of STIMULAN and complete pain relief 9 months after treatment. He remains very active and infection free.


For indications, contraindications, warnings and precautions see Instructions for Use.  The treating physician is responsible for deciding the type and quantity of antibiotic used.  Concurrent use of locally administered antibiotics may affect setting time.

The mixing of antibiotics with the STIMULAN Kit / STIMULAN Rapid Cure device is considered off-label usage of the medicinal product. To do so is at the professional risk of the surgeon / healthcare professional.

This brochure may include the use of STIMULAN or techniques that go beyond the current clearance/ approval granted by the relevant regulatory authority. Please contact your local representative for further information.

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Patents granted: GB2367552, EP 1204599 B1, US 6780391, EP 2594231 B1, US 8883063, CN ZL201210466117.X, GB2496710, EP 3058899 B1

Patents pending: GB1502655.2, US 15/040075, CN 201610089710.5, US 15/288328, GB1704688.9, EP 18275044.8, US 15/933936