Case study

Transform infected humerus

Courtesy of Courtesy of Mr Alan Norrish Consultant Orthopaedic Surgeon; Mr Dimitrios Giotikas, Specialist Orthopaedic Surgeon
Cambridge, UK

Clinical particulars

44-year-old female presented with persistent and severe pain of the right arm. She had a history of infection following a nailing of the humerus 15 years ago. She has grown Staphylococcus aureus in the past and has had a number of flare-ups over the years. 7 years ago, she had a fenestration and a sequestrum removed, and MSSA was isolated.


She was treated with an open sequestrectomy through a bone window, made through a deltopectoral approach. 10cc of STIMULAN beads were administered to complement dead space management. A suction drain was placed for 24 hours. Systemic antibiotics were administered intravenously for 6 weeks.


At 6 month follow-up, the patient had returned to normal activities without symptoms or signs suggesting persistence or recurrence of infection. CRP = 1. On the x-ray, the bone window and cavity appeared filled with newly formed bone.

2 years post-operatively no recurrence of infection had occurred.


For indications, contraindications, warnings and precautions see Instructions for Use.  The treating physician is responsible for deciding the type and quantity of antibiotic used.  Concurrent use of locally administered antibiotics may affect setting time.

The mixing of antibiotics with the STIMULAN Kit / STIMULAN Rapid Cure device is considered off-label usage of the medicinal product. To do so is at the professional risk of the surgeon / healthcare professional.

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Patents granted: GB2367552, EP 1204599 B1, US 6780391, EP 2594231 B1, US 8883063, CN ZL201210466117.X, GB2496710, EP 3058899 B1

Patents pending: GB1502655.2, US 15/040075, CN 201610089710.5, US 15/288328, GB1704688.9, EP 18275044.8, US 15/933936

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